THERAPEUTIC CLASS

Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

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Cigarette smoking is associated with numerous diseases and poses a serious challenge to the current healthcare system worldwide. Smoking impacts both innate and adaptive immunity and plays dual roles in regulating immunity by either exacerbation of pathogenic immune responses or attenuation of defensive immunity. Adaptive immune cells affected by smoking mainly include T helper cells (Th1/Th2/Th17), CD4+CD25+ regulatory T cells, CD8+ T cells, B cells and memory T/B lymphocytes while innate immune cells impacted by smoking are mostly DCs,
macrophages and NK cells

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Carboplatin
Cisplatin
Allergy & Immune System
Paclitaxel

Specific Detail Info

Oncotarget, 2017, Vol. 8, (No. 1), pp: 268-284

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