THERAPEUTIC CLASS
Cigarette Smoke Effects on Innate Immune Mechanisms in the Nasal Mucosa Potential Effects on the Microbiome
It is well established that exposure to cigarette smoke (CS), through active smoking and through exposure to secondhand smoke, has immunosuppressive effects, yet how this might affect the microbiome is not known. In this manuscript we focus on the effects of CS on innate host defense response, with particular emphasis on the role of epithelial cells and mucosal immune responses in the nose and the potential effects on the microbiome
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