The Role of MicroRNAs in Myocardial Infarction: From Molecular Mechanism to Clinical Application

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The Role of MicroRNAs in Myocardial Infarction: From Molecular Mechanism to Clinical Application

Sun T - Personal Name;

MicroRNAs (miRNAs) are a class of small single-stranded and highly conserved non-coding RNAs, which are closely linked to cardiac disorders such as myocardial infarction (MI), cardiomyocyte hypertrophy, and heart failure. A growing number of studies have demonstrated that miRNAs
determine the fate of the heart by regulating cardiac cell death and regeneration after MI. A deep understanding of the pathophysiology of miRNA dependent regulatory pathways in these processes is required. The role of miRNAs as diagnostic, prognostic, and therapeutic targets also needs to be explored in order to utilize them in clinical settings

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Language: English
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Subject(s): Cardiovascular & Hematopoeiteic System
Specific Detail Info: Int. J. Mol. Sci. 2017, 18, 745
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