THERAPEUTIC CLASS

Heparin induced thrombocytopenia: diagnosis and management update

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Heparin-induced thrombocytopenia (HIT) is a potentially devastating immune mediated adverse drug reaction caused by
the emergence of antibodies that activate platelets in the presence of heparin. Despite thrombocytopenia, bleeding is
rare; rather, HIT is strongly associated with thromboembolic complications involving both the arterial and venous systems. A
number of laboratory tests are available to confirm the diagnosis; however, when HIT is clinically suspected, treatment
should not be withheld pending the result.

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: .,

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Language

English

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NONE

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Subject(s)

Cardiovascular & Hematopoeiteic System

Specific Detail Info

Postgrad Med J 2007;83:575–582

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