THERAPEUTIC CLASS

Potential Metastatic Locoregional Lymph Nodes on Squamous Cell Carcinoma Larynx: Examination of Biomarker Expression HPV, EGFR, MMP-9, TIMP-1, VEGF, E-Cadherin, and Collagen Type IV

---

Biomarkers to predict locoregional lymph nodes metastasis is not yet accurate until now. The
number of occult metastasis in laryngeal carcinoma varies between 1–65%. A tumor biomarker that can give
information on the existence of locoregional lymph node involvement in patients with or without signs of clinical
locoregional lymph node involvement, as guidelines whether selective neck dissection is needed in N0 cases. For
patients that need additional treatment biomarkers that are correlated with aggresivity and metastasis prediction
such as EGFR, MMP-9, TIMP-1, VGEF, E-cadherin, collagen Type IV and HPV are also needed to predict the
outcome of patients with or without lymph node metastasis.

---

Availability

Detail Information

Series Title

-

Call Number

-

Publisher

: .,

Collation

-

Language

English

ISBN/ISSN

-

Classification

NONE

Content Type

LITERATURE

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Oncology

Specific Detail Info

Advanced Science Letters Vol. 24, 6802–6806, 2018

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment