PRODUCT LITERATURE

Pharmacokinetics of Moxifloxacin and Levofloxacin in Intensive Care Unit Patients Who Have Acute Renal Failure and Undergo Extended Daily Dialysis

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Extended daily dialysis (EDD) is increasingly popular in the treatment of acute renal failure (ARF). EDD could remove drugs
to a much different degree compared with intermittent standard hemodialysis or continuous renal replacement therapies;
however, there are only scarce data on how EDD influences the pharmacokinetics of frequently used drugs. The aim of this
study was to determine the pharmacokinetics of two quinolone antibiotics in patients who had anuric ARF and were being
treated with EDD. Adult patients who were in the intensive care unit at a tertiary care university hospital and receiving
moxifloxacin (n
10) or levofloxacin (n
5) therapy were included

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Publisher

: .,

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Language

English

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Classification

NONE

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Edition

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Subject(s)

Molcin

Specific Detail Info

Clin J Am Soc Nephrol 1: 1263–1268, 2006

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