Image of Pharmacokinetic Profile of Levofloxacin following Once-Daily 500-Milligram Oral or Intravenous Doses

LITERATURE

Pharmacokinetic Profile of Levofloxacin following Once-Daily 500-Milligram Oral or Intravenous Doses


The pharmacokinetics of once-daily oral levofloxacin (study A) or intravenous levofloxacin (study B) in 40 healthy male volunteers were investigated in two separate randomized, double-blind, parallel-design, placebocontrolled studies. Levofloxacin at 500 mg or placebo was administered orally or intravenously as a single dose
on day 1; daily oral or intravenous dosing resumed on days 4 to 10. In a third study (study C), the comparability of the bioavailabilities of two oral and one intravenous levofloxacin formulations were investigated with 24 healthy male subjects in an open-label, randomized, three-way crossover study


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Volequin-001Titan CenterAvailable

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English
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NONE
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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,1997 Vol. 41, No. 10: 2256–2260
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