PRODUCT LITERATURE

Pharmacokinetic Profile of Levofloxacin following Once-Daily 500-Milligram Oral or Intravenous Doses

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The pharmacokinetics of once-daily oral levofloxacin (study A) or intravenous levofloxacin (study B) in 40 healthy male volunteers were investigated in two separate randomized, double-blind, parallel-design, placebocontrolled studies. Levofloxacin at 500 mg or placebo was administered orally or intravenously as a single dose
on day 1; daily oral or intravenous dosing resumed on days 4 to 10. In a third study (study C), the comparability of the bioavailabilities of two oral and one intravenous levofloxacin formulations were investigated with 24 healthy male subjects in an open-label, randomized, three-way crossover study

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: .,

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Language

English

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Classification

NONE

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Edition

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Subject(s)

Volequin

Specific Detail Info

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,1997 Vol. 41, No. 10: 2256–2260

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