THERAPEUTIC CLASS

Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE

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Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) in which the immune system damages
the protective insulation surrounding the nerve fibers that project from neurons. A hallmark of MS and its animal model,
experimental autoimmune encephalomyelitis (EAE), is autoimmunity against proteins of the myelin sheath. Most studies in this field
have focused on the roles of CD4+ T lymphocytes, which form part of the adaptive immune system as both mediators and
regulators in disease pathogenesis

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: .,

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Language

English

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NONE

Content Type

LITERATURE

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Subject(s)

Allergy & Immune System

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