Image of Thermosensitive chitosan–Pluronic hydrogel as an injectable cell delivery carrier for cartilage regeneration

LITERATURE

Thermosensitive chitosan–Pluronic hydrogel as an injectable cell delivery carrier for cartilage regeneration


Injectable hydrogels have been studied for potential applications for articular cartilage regeneration. In this study, a thermosensitive
chitosan–Pluronic (CP) hydrogel was designed as an injectable cell delivery carrier for cartilage regeneration. The CP conjugate was synthesized
by grafting Pluronic onto chitosan using EDC/NHS chemistry. The sol–gel phase transition and mechanical properties of the CP
hydrogel were examined by rheological experiments. The CP solution underwent a sol–gel transition around 25 C at which the storage
modulus (G0) approaches 104 Pa, highlighting the potential of this material as an injectable scaffold for cartilage regenerationInjectable hydrogels have been studied for potential applications for articular cartilage regeneration. In this study, a thermosensitive
chitosan–Pluronic (CP) hydrogel was designed as an injectable cell delivery carrier for cartilage regeneration. The CP conjugate was synthesized
by grafting Pluronic onto chitosan using EDC/NHS chemistry. The sol–gel phase transition and mechanical properties of the CP
hydrogel were examined by rheological experiments. The CP solution underwent a sol–gel transition around 25 C at which the storage
modulus (G0) approaches 104 Pa, highlighting the potential of this material as an injectable scaffold for cartilage regeneration


Availability

Mediclore-004Titan CenterAvailable

Detail Information

Series Title
-
Call Number
-
Publisher : .,
Collation
-
Language
English
ISBN/ISSN
-
Classification
NONE
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Specific Detail Info
Acta Biomaterialia 5 (2009) 1956–1965
Statement of Responsibility

Other version/related

No other version available


File Attachment



Information


RECORD DETAIL


Back To Previous