THERAPEUTIC CLASS
Hypertension, left ventricular hypertrophy, and sudden cardiac death
Hypertension (HTN) is among the most common, noncommunicable disease in the world. Approximately 80 million people (32.6%) in the United States [1] and one billion worldwide suffer from HTN [2], and the prevalence may be even higher as the diagnosis is based on an objective test (i.e., blood pressure measurement). Longterm HTN leads to hypertensive heart disease, and is the result of anatomical and functional changes in the cardiovascular system (which is a cardiovascular sequelae of HTN) and is defined as left ventricular hypertrophy (LVH), left atrial enlargement, left ventricular diastolic dysfunction, functional mitral regurgitation and neurohormonal changes [3]
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