THERAPEUTIC CLASS

TLR2 agonism reverses chemotherapy-induced neutropenia in Macaca fascicularis

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Neutropenia is a common consequence of radiation and chemotherapy in cancer patients. The resulting immunocompromised patients become highly susceptible to potentially life-threatening infections. Granulocyte colony-stimulating factor (G-CSF) is known to stimulate neutrophil production and is widely used as a treatment of chemotherapy-induced
neutropenia. A small-molecule G-CSF secretagogue without a requirement for refrigerated supply chain would offer a more convenient and cost-effective treatment of chemotherapy-induced neutropenia.

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: .,

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English

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NONE

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Subject(s)

Oncology

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