THERAPEUTIC CLASS
Raynaud's Disease in Children
Six children with primary Raynaud's disease have been studied with plethysmography and multiple-site skin-temperature readings. All six were free of systemic disease. Each demonstrated the characteristic sequence of pallor, cyanosis, and rubor when subjected to generalized cold, but application of local cold produced only modest reduction in skin temperature and digital pulse. Only one child had a history of vasospastic symptoms associated with emotional stimuli, and she was the only one in whom an emotional challenge was able to produce Raynaud's phenomenon during the physiological studies
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