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Role of the intrarenal renin–angiotensin system in the progression of renal disease


The intrarenal renin–angiotensin system (RAS) has many well-documented pathophysiologic functions in both blood pressure regulation and renal disease development. Angiotensin II (Ang II) is the major bioactive product of the RAS. It induces inflammation, renal cell growth, mitogenesis, apoptosis, migration, and differentiation


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English
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NONE
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Pediatr Nephrol
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