THERAPEUTIC CLASS
Twin-twin transfusion syndrome (TTTS)
The etiology of TTTS is connected with the architecture of the placenta, and intertwine vascular connections
known as anastomoses within the placenta. Actually all MC placentas have anastomoses that connect the fetal
circulations. Fortunately, not all MC twins develop TTTS. Three main types of anastomoses might be distinguished:
venovenous (VV), arterioarterial (AA), and arteriovenous (AV). The imbalance of blood flow through the
placental anastomoses leads to volume depletion in the donor twin, with oliguria and oligohydramnios, and to
volume overload in the recipient twin, with polyuria and polyhydramnios
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