THERAPEUTIC CLASS

Natural Antibodies Bridge Innate and Adaptive Immunity

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Natural Abs, belonging to isotypes IgM, IgG3, and IgA, were discovered nearly half a century ago. Despite knowledge about the role of the polyreactive natural IgM in pathogen elimination, B cell survival and homeostasis, inflammatory diseases, and autoimmunity, there is a lack of clarity about the physiological role of natural IgG and natural IgA because they appear
incapable of recognizing Ags on their own and are perceived as nonreactive

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Detail Information

Series Title

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Call Number

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Publisher

: .,

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Carrier Type

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Edition

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Subject(s)

HBIG
Moprin
Privigen
Biobran
Allergy & Immune System
Beprin

Specific Detail Info

The Journal of Immunology, 2015, 194: 13–20

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