THERAPEUTIC CLASS
Immune checkpoint therapy for non-smallcell lung cancer: an update
The role of immunotherapy in treatment of non-small-cell lung cancer (NSCLC)
has been gaining interest over the past few years. This has been driven primarily
by promising results from trials evaluating antagonist antibodies that target coinhibitory
immune checkpoints expressed on tumor cells and immune cells within the
tumor microenvironment. Immune checkpoints exist to dampen or terminate immune
activity to guard against autoimmunity and allow for self-tolerance
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