THERAPEUTIC CLASS
Surgical management of advanced non-small cell lung cancer
More than 75% of the cases of non-small cell lung cancer (NSCLC) are diagnosed in advanced
stages (IIIA-IV). Although in these patients the role of surgery is unclear, complete tumor resection can
be achieved in selected cases, with good long-term survival. In this review, current indications for surgery
in advanced NSCLC are discussed. In stage IIIA (N2), surgery after induction chemotherapy seems to be
the best option. The indication of induction chemotherapy plus radiotherapy is debatable due to potential
postoperative complications but recently reported experiences have not shown a higher postoperative
risk in patients after chemo and radiotherapy induction even if pneumonectomy is performed
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