THERAPEUTIC CLASS

The Role of Vildagliptin in the Therapy of Type 2 Diabetic Patients with Renal Dysfunction

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Diabetes is the leading cause of chronic kidney disease, and even in the absence of albuminuria, decreased renal function in type 2 diabetes mellitus (T2DM) patients increases the risk for major adverse cardiovascular events and death.
The evidence derived from recent studies suggests that intensive glucose control not only reduces the risk for microalbuminuria and macroalbuminuria but may also decrease the rate of decline of glomerular filtration rate (GFR). Although insulin therapy is widely used in patients with T2DM and renal disease, metabolic control is particularly difficult to achieve and manage because of the limited therapeutic options and the frequent comorbidities seen in this population

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: .,

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Language

English

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NONE

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Subject(s)

Endocrine & Metabolic system

Specific Detail Info

Diabetes Ther

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