Image of SERPINA1 and MAN1B1 polymorphisms are not linked to severe liver disease in a French cohort of alpha-1 antitrypsin
deficiency children

LITERATURE

SERPINA1 and MAN1B1 polymorphisms are not linked to severe liver disease in a French cohort of alpha-1 antitrypsin deficiency children


Fifteen to twenty percent of alpha-1
antitrypsin deficiency patients
(A1ATD) have a severe liver outcome (portal hypertension -PHT)
during childhood.
Since they all share the same ZZ SERPINA1 genotype and that environmental
factors such as alcohol cannot be advanced, the presence of modifier genes is now
well recognized. SNPs located on the SERPINA1 and MAN1B1 genes have already
been tested in very few studies with contradictory or not replicated results


Availability

REQJ473-01Titan CenterAvailable

Detail Information

Series Title
-
Call Number
-
Publisher : .,
Collation
-
Language
English
ISBN/ISSN
-
Classification
NONE
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Specific Detail Info
Liver International. 2017;1–4.
Statement of Responsibility

Other version/related

No other version available


File Attachment



Information


RECORD DETAIL


Back To Previous