THERAPEUTIC CLASS

An Introduction to Nitric Oxide Sensing and Response in Bacteria

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Nitric oxide (NO) is a radical gas that has been intensively studied for its role as a bacteriostatic agent. NO reacts in complex ways with biological molecules, especially metal centers and other radicals, to generate other bioactive compounds that inhibit
enzymes, oxidize macromolecules, and arrest bacterial growth. Bacteria encounter not only NO derived from the host during infection but also NO derived from other bacteria and inorganic sources.

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English

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NONE

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Anti Infectives

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Advances in Applied Microbiology 2014 Volume 87

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