The use of fondaparinux in pregnancy

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The use of fondaparinux in pregnancy

Venous thromboembolism (VTE) remains a major cause of morbidity and mortality in pregnancy. Although relatively safe, hypersensitivity reactions to low-molecular weight heparins (LMWHs) are frequently seen in pregnant women, with
a reported 20% incidence in this cohort (Bank et al, 2003; Schindewolf et al, 2013). Fondaparinux is a synthetic pentasaccharide
that has been extensively studied in thromboprophylaxis and treatment of VTE and which may be used as an alternative in these circumstances. This study describes the use of fondaparinux in pregnant women who experienced heparin allergy in our institution over an 8-year period.

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Language: English
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Subject(s): Diviti
Specific Detail Info: British Journal of Haematology, 2015, 168, 757–768
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