A Review of Doripenem for the Treatment of Serious Bacterial Infections

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A Review of Doripenem for the Treatment of Serious Bacterial Infections

Redman R - Personal Name;

Doripenem is a carbapenem bactericidal agent that demonstrates in vitro activity against a wide variety of Gram-negative and Gram-positive pathogens. In vitro data show that doripenem combines the intrinsic activity of meropenem against Gram-negative pathogens with the intrinsic activity of imipenem against Gram-positive pathogens. The availability of doripenem is particularly welcome in the current setting of increased resistance among Gram-negative pathogens including Pseudomonas aeruginosa, Acinetobacter species, and extended-spectrum β-lactamase-producing Enterobacteriaceae

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Language: English
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Subject(s): DRM
Specific Detail Info: Clinical Medicine Reviews in Therapeutics 2010:2 201–227
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