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PRODUCT LITERATURE

Cefdinir: A Review of its Use in the Management of Mild-to-Moderate Bacterial Infections

Perry CM - Personal Name;

Cefdinir (Omnicef) is an oral third-generation cephalosporin with good in vitro activity against many pathogens commonly causative in community-acquired infections. The drug provides good coverage against Haemophilus influenzae,
Moraxella catarrhalis and penicillin-susceptible Streptococcus pneumoniae, the most common respiratory tract pathogens. Cefdinir is stable to hydrolysis by commonly occurring plasmid-mediated β-lactamases and retains good activity
against β-lactamase-producing strains of H. influenzae and M. catarrhalis. The drug distributes into various tissues (e.g. sinus and tonsil) and fluids (e.g. middle ear), and has a pharmacokinetic profile that allows for once- or twice-daily administration.


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English
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Omnicef
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Drugs 2004; 64 (13): 1433-1464
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