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LITERATURE

Clopidogrel Use and Long-term Clinical Outcomes After Drug-Eluting Stent Implantation


An observational study examining consecutive patients receiving intracoronary stents at Duke Heart Center, a tertiary care medical center in Durham, NC, between January 1, 2000, and July 31, 2005, with follow-up contact at 6, 12, and 24 months through September 7, 2006. Study population included 4666 patients undergoing initial percutaneous coronary intervention with BMS (n=3165) or DES (n=1501). Landmark analyses were performed among patients who were eventfree
(no death, myocardial infarction [MI], or revascularization) at 6- and 12-month follow-up. At these points, patients were divided into 4 groups based on stent type and self-reported clopidogrel use: DES with clopidogrel, DES without clopidogrel, BMS
with clopidogrel, and BMS without clopidogrel


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English
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JAMA. 2007;297:159-168
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