THERAPEUTIC CLASS

Etiology of Peptic Ulcer Disease

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Peptic ulcer (PU) is defect in the gastrointestinal mucosa usually located in the stomach and duodenum, but it can develop in any portion of the gastrointestinal tract that is exposed to acid and pepsin in sufficient concentration and duration. Histologically, ulcers are defined as necrotic mucosal defects that extend through the muscularis mucosa and into submucosa,
whereas superficial necrotic defects are considered as erosions [1]. PU disease is one of the main prevalent and still unresolved medical problem that faces many patients of both sexes worldwide and is an important cause of morbidity and healthcare costs.

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: .,

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English

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NONE

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Gastrointestinal & Hepatobiliary System

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www.smgebooks.com

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