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Intramuscular High-Dose Triamcinolone Acetonide in the Treatment of Severe Chronic Asthma


We describe our experience with administering intramuscular triamcinolone acetonide to 22 steroiddependent patients with asthma. These patients represent the minority of those with asthma whose disease is characterized by frequent emergency department visits, hospital admissions, and long-term dependency on oral corticosteroid therapy. The participants were randomly assigned to 2 treatment groups, one group receiving 120 mg of intramuscular triamcinolone acetonide, the second receiving 360 mg as a series of three 120-mg daily doses.


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English
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West j Med 1997; 157:322-329
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