THERAPEUTIC CLASS

G-CSF and GM-CSF in Neutropenia

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Granulocyte Colony Stimulating Factor (G-CSF) and Granulocyte/Macrophage Colony Stimulating Factor (GM-CSF) are used widely to promote the production of granulocytes or antigen presenting cells (APC). The Food and Drug Administration approved G-CSF (filgrastim) for the treatment of congenital and acquired neutropenias and for mobilization of peripheral hematopoietic progenitor cells for stem cell transplantation. A polyethylene glycol modified (PEGylated) form of G-CSF is approved for the treatment of neutropenias

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Detail Information

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Publisher

: .,

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Language

English

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Classification

NONE

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Subject(s)

Oncology

Specific Detail Info

J Immunol. 2015 August 15; 195(4): 1341–1349

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