THERAPEUTIC CLASS

HLA antigens in individuals with down syndrome and alopecia areata

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Seventy per cent of evaluated individuals in the DS and AA group were male; presented mean age of 18.6 (SD ± 7.2) years and 70% were Caucasian. We observed involvement of the scalp, with a single lesion in 10% and multiple in 90% of subjects. It was
observed that there is no significant difference in the frequency distributions of the alleles HLA loci A, B, C, DRB1 and DQB1 of subjects studied. However, according to Fisher’s exact test, there is a trend (P = 0.089) of DS group to present higher proportions of HLA-A 36 and HLA-B 15 than the AA group and AA and DS group.

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: .,

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Language

English

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NONE

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Other Therapeutic Class

Specific Detail Info

World J Clin Cases 2014 October 16; 2(10): 541-545

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