THERAPEUTIC CLASS

Novel insights into acute kidney injuryechronic kidney disease continuum and the role of renineangiotensin system

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Acute kidney injury (AKI) is an independent risk factor for chronic kidney disease (CKD). If injury is mild, a repair process can be adaptive and lead to complete renal recovery. However, severe injury will be accompanied by a maladaptive repair which usually leads to nephron loss, fibrosis, vascular rarefaction, and chronic inflammation. Although various mechanisms underlying AKI-CKD transition have been explored, no intervention has been proved effective to block the transition until very recently

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Cardiovascular & Hematopoietic System

Specific Detail Info

Journal of the Formosan Medical Association (2017) xx, 1e8

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