THERAPEUTIC CLASS

DLBS1033, A Protein Extract from Lumbricus rubellus, Possesses Antithrombotic and Thrombolytic Activities

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The medicinal value of earthworm has been widely known since the history of Asian ancient medicine. This present study aims
to determine the mechanism of action and effect of a standardized extract of Lumbricus rubellus named as DLBS1033. The
fibrinogen degradation, antiplatelet aggregation, and ex vivo antithrombotic assay using human blood were performed to study
antithrombotic activity. Fibrin plate and clot lysis assay were also done to examine thrombolytic properties. DLBS1033 was found to possess fibrinogenolytic activity on α-, β-, and γ-chain of fibrinogen

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Publisher

: .,

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

Therapeutic Class

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Edition

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Subject(s)

Cardiovascular & Hematopoietic System
Disolf

Specific Detail Info

Journal of Biomedicine and Biotechnology Volume 2011

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