THERAPEUTIC CLASS

The role of nitric oxide in cardiovascular diseases

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Nitric oxide (NO) is a gaseous lipophilic free radical cellular messenger generated by three distinct isoforms of nitric oxide synthases (NOS), neuronal (nNOS), inducible (iNOS) and endothelial NOS (eNOS). NO plays an important role in the protection against the onset and progression of cardiovascular disease. Cardiovascular disease is associated with a number of different disorders including hypercholesterolaemia, hypertension and diabetes. The underlying pathology for most cardiovascular diseases is atherosclerosis, which is in turn associated with endothelial dysfunctional

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: .,

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Language

English

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NONE

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Subject(s)

Cardiovascular & Hematopoietic System
NTG

Specific Detail Info

Molecular Aspects of Medicine 26 (2005) 33–65

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