THERAPEUTIC CLASS

The role of tumour necrosis factor in hepatitis B infection: Jekyll and Hyde

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Chronic hepatitis B (CHB) is a major health problem worldwide and is associated with significant long-term morbidity and mortality. The hepatitis B virus (HBV) is a hepatotropic virus that is capable of integrating in the host nucleus permanently resulting in lifelong infection. To date, there is no definitive cure for HBV, as our current treatments cannot eradicate the viral
reservoir that has integrated in the liver. Elucidating the immunopathogenesis is key to finding a therapeutic target for HBV as the virus is not in itself cytopathic but the immune response to the virus causes the majority of the cellular injury

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: .,

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Language

English

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NONE

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Subject(s)

SNMC
Gastrointestinal & Hepatobiliary System
Inbumin
Human Albumin Behring
Albuminar
Albapure

Specific Detail Info

Clinical & Translational Immunology (2016) 5, e115

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