THERAPEUTIC CLASS

GNAS: A New Nephrogenic Cause of Inappropriate Antidiuresis

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Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is the mirror image of nephrogenic diabetes insipidus (NDI): in NDI, the kidneys cannot concentrate the urine, whereas in
NSIAD, urinary dilution is impaired, independent of the presence or absence of vasopressin. Consequently, patients with NDI are at risk of hypernatremic dehydration, whereas
hyponatremia is a typical manifestation of NSIAD, mimicking the syndrome of inappropriate antidiuresis.

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: .,

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Language

English

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Classification

NONE

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Subject(s)

Genito -Urinary System

Specific Detail Info

JASN 2019;30

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