Cellular and molecular mechanisms of renal fibrosis

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Cellular and molecular mechanisms of renal fibrosis

Liu Y - Personal Name;

Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of prognosis and a major determinant of renal insufficiency. Irrespective of the initial causes, renal fibrogenesis is a dynamic and converging process that consists of four overlapping phases: priming, activation, execution and progression.

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Language: English
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Subject(s): Aminefron
Cardiovascular & Hematopoietic System
Specific Detail Info: Nat. Rev. Nephrol. 7, 684–696 (2011)
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