Image of Photosensitive epilepsy : Robust clinical efficacy of a selective GABA potentiator

LITERATURE

Photosensitive epilepsy : Robust clinical efficacy of a selective GABA potentiator


The objective of this phase 2a study was to assess the activity of PF-06372865, a positive
allosteric modulator (PAM) of α2/3/5 subunit-containing GABAA receptors with minimal
activity at α1-containing receptors, which are believed to mediate many of the adverse events
associated with benzodiazepines, in the epilepsy photosensitivity model as a proof-of-principle
of efficacy


Availability

REQJ466-03Titan CenterAvailable

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Language
English
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NONE
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Specific Detail Info
Neurology 2019
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