PRODUCT LITERATURE

Darbepoetin alpha in lower-than-equimolar doses maintains haemoglobin levels in stable haemodialysis patients converting from epoetin alpha/beta

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The conversion of patients on stable epoetin therapy to darbepoetin alpha is usually carried
out according to the ‘1 mg darbepoetin¼200U epoetin’ rule, which is based on the protein content of the two compounds. Since several observations have suggested that this conversion factor leads to an overestimate of the required darbepoetin dose, the present multicentre
study was designed to assess the true conversion ratio by prospectively evaluating the change in darbepoetin alpha dose after conversion from epoetin, which was required to keep haemoglobin (Hb) stable.

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: .,

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Language

English

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NONE

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Subject(s)

NESP

Specific Detail Info

Nephrol Dial Transplant (2008) 23: 301–308

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