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LITERATURE

Comparison of the Lipid-Lowering Effects of Pitavastatin 4mg Versus Pravastatin 40mg in Adults With Primary Hyperlipidemia or Mixed (Combined)Dyslipidemia: A PhaseIV, Prospective, US, Multicenter, Randomized, Double-blind, Superiority Trial


Results froma Phase III, European, non-inferiority trial in elderly (age Z65 years) patients with primary hyperlipidemia or mixed(combined) dyslipidemia demonstrated significantly greater reductions in LDL-C for pitavastatin versus pravastatin across 3pair-wise dose comparisons (1mgvs10mg,2 mgvs20mg, and4mgvs40mg, respectively). The present study investigated whether pitavastatin 4mg is superior to pravastatin 40mg in LDL-Creductionin adults (18–80 years old)withprimary hyperlipidemia or mixed(combined)dyslipidemia.


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English
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NONE
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Clin Ther. 2014;36:1211–1222
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