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Clinical Efficacy of Pitavastatin, a New 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitor, in Patients with Hyperlipidemia

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Pitavastatin (CAS 147526-32-7, NK-104), the first totally synthetic 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor discovered in Japan, was examined. Pitavastatin significantly decreased the serum levels of total cholesterol (TC) and low-density lipoprotein
cholesterol (LDL-C) at doses of 1 mg/day or more, and significant dose-dependence
of the effect of this drug was observed within the dose range from 1 mg/day to 4 mg/day.

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: .,

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Language

English

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NONE

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Subject(s)

Vitor

Specific Detail Info

Arzneim.-Forsch./Drug Res. 52, No. 4, 251−255 (2002)

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