Strategies to increase nitric oxide signalling in cardiovascular disease

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Strategies to increase nitric oxide signalling in cardiovascular disease

Lundberg JO - Personal Name;

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central nervous systems, and crucial steps in the regulation of NO bioavailability in health and disease are well characterized. Although early approaches to therapeutically modulate NO bioavailability failed in clinical trials, an enhanced understanding of fundamental subcellular signalling has enabled a range of novel therapeutic approaches to be identified

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Language: English
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Subject(s): Cardiovascular & Hematopoietic System
Nevodio
NTG
Hyperil
Specific Detail Info: Nature Reviews Drug Discovery 2015
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