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A Comparative Tolerance Study of Terfenadine - Pseudoephedrine Combination Tablets and Pseudoephedrine Tablets in Patients with Allergic or Vasomotor Rhinitis


In this multicentre , double-blind, randomized, parallel group study, 315 patients with allergic or vasomotor rhinitis were treated on a twice daily dosing schedule with either a 60 mg terfenadine -120 mg pseudoephedrine hydrochloride combination or 120 mg pseudoephedrine hydrochloride (extended release) for 2 weeks. Noclinically significant differences between the two groups were noted in body weight, temperature, respiration rate or blood pressure following the treatment period.


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English
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The Journal of International Medical Research 1988; 16: 420-427
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