PRODUCT LITERATURE
Comparative Efficacy of Valsartan and Olmesartan in Mild-to-Moderate Hypertension: Results of 24-Hour Ambulatory Blood Pressure Monitoring
The aim of this prospective, randomized, open-label, blinded endpoint (PROBE) study was to compare the antihypertensive efficacy of 2 angiotensin II (AII) recep-tor antagonists with different pharmacologic profiles, valsartan and olmesartan, in patients with mild-to-moderate essential hypertension. After an initial 2-week washout period, 114 patients (64 men, 50 women; aged 35–70 years) were ran-domly assigned to receive valsartan 160 mg or olmesartan 20 mg once daily for 8 weeks.
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