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Otilonium bromide enhances sensory thresholds of volume and pressure in patients with irritable bowel syndrome


Visceral hyperalgesia has been suggested to play a role in the development of symptoms presented by irritable bowel syndrome patients. Otilonium bromide was developed to block smooth muscle Ca release to control crampingpain of these patients. Aims: to determine whether otilonium bromide can influence sensory thresholds of patients sufferingfrom irritable bowel syndrome.


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English
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NONE
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Journal of Physiology - Paris 95 (2001) 153–156
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