PRODUCT LITERATURE

Effects of the Disaccharidase Inhibitor Acarbose on Meal and Intravenous Glucose Tolerance in Normal Man

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To determine whether the effects of the disaccharidase inhibitor Acarbose on glucose tolerance could be solely explained via an action on intestinal nutrient absorption, the effects of this agent and placebo (100 mg p.0.) on intravenous and postprandial glucose tolerance were compared in six normal subjects. Acarbose significantly diminished plasma glucose, insulin, and astrointestinal inhibitory polypeptide responses following meal ingestion without affecting plasma glucagon and pancreatic polypeptide responses, but had no effect on plasma glucose and insulin responses following intravenous injection of glucose.

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Series Title

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Publisher

: .,

Collation

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Language

English

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Classification

NONE

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Media Type

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Carrier Type

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Edition

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Subject(s)

Eclid

Specific Detail Info

Metabolism, Vol. 3 1, No. 8 (August), 1992

Statement of Responsibility

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