PRODUCT LITERATURE

EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision

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Most large RCTs included patients with diabetic polyneuropathies and postherpetic neuralgia, while an increasing number of smaller studies explored other conditions. Drugs generally have similar efficacy in various conditions, except in trigeminal neuralgia, chronic radiculopathy and HIV neuropathy, with level A evidence
in support of tricyclic antidepressants (TCA), pregabalin, gabapentin, tramadol and opioids (in various conditions), duloxetine, venlafaxine, topical lidocaine and capsaicin patches (in restricted conditions). Combination therapy appears useful for TCAgabapentin and gabapentin-opioids (level A).

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: .,

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Language

English

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NONE

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Subject(s)

Gapenal

Specific Detail Info

European Journal of Neurology 2010, 17: 1113–1123

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