THERAPEUTIC CLASS

Murine model of TB meningitis

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Central nervous system (CNS) infections caused by Mycobacterium tuberculosis
(MTB) are the most severe forms of extrapulmonary TB (EPTB) due to high levels of mortality
and neurological morbidity. Limited studies are available on CNS-TB animal-model
development, despite the steady rise in cerebral-TB cases in India over the past decade.
This study describes the development of a murine model of CNS-TB using a clinical strain
(C3) isolated from the cerebrospinal fluid (CSF) of CNS-TB patients.

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Series Title

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Publisher

: .,

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

Therapeutic Class

Media Type

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Carrier Type

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Edition

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Subject(s)

Anti Infectives

Specific Detail Info

I n t e r n a t i o n a l J o u r n a l o f My c o b a c t e r i o l o g y 5 ( 2 0 1 6 ) S 1 7 8

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