THERAPEUTIC CLASS
Autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and one of
the most common causes of end-stage kidney disease. Multiple clinical manifestations, such as enlarged kidneys
filled with growing cysts, hypertension, and multiple extrarenal complications, including liver cysts, intracranial
aneurysms, and cardiac valvular disease, show that ADPKD is a systemic disorder
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