PRODUCT LITERATURE

Changes in Concentrations of Free Propofol by Modification of the Solution

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Because free propofol is thought to be responsible for
pain on injection, we investigated the changes in concentrations of free propofol by modifying two kinds of
propofol products in a medium- and long-chain triglyceride (MCT/LCT) emulsion and in an LCT emulsion.
The techniques used in this study were 1) mixing 2%
lidocaine (10:1), 2) mixing 5% dextrose in acetated Ringer’s solution to reduce pH (10:1), and 3) changing the
temperature to 4°, 20°, and 36°C.

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: .,

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English

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NONE

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Subject(s)

RECOFOL N

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