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Gastrointestinal tolerability of extended-release metformin tablets compared to immediate release metformin tablets: resultsrnof a retrospective cohort study

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Metformin, a biguanide antihyperglycemic medication, lowers blood glucose in patients with type 2 diabetes with minimal risk of hypoglycemia. Most common side effects include diarrhea, nausea and vomiting. Extended-release metformin (Glucophage XR)*, a once-daily tablet using the patented GelShield Diffusion System release mechanism, may be better tolerated than immediate-release metformin (Glucophage). This retrospective chart review examined the overall gastrointestinal (GI) tolerability of both formulations

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: .,

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Language

English

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NONE

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Subject(s)

GLUMIN XR

Specific Detail Info

CURRENT MEDICAL RESEARCH AND OPINION 2004; VOL. 20, NO. 4, 2004, 565–572

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