Image of New Therapeutical Indications of Ursodeoxycholic Acid

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New Therapeutical Indications of Ursodeoxycholic Acid


Until the 1980s the role of bile acids in the initiation of liver injury in man was only suspected on the basis of the toxicity of whole bile and bile salts, and of studies showing elevations in serum and tissue levels of bile salts in liver diseases. The beneficial effects of ursodeoxycholic acid (UDCA) in primary biliary cirrhosis have provided the first firm evidence that bile acids may in some way be related to injury in man


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Romanian Journal of Gastroenterology 2005 Vol.14 No.3, 259-266
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