THERAPEUTIC CLASS
Safety of New Oral Anticoagulants for Patients with Chronic Kidney Disease
In daily practice, chemical substances called “direct oral anticoagulants” or DOACs are more convenient
to administer when set beside vitamin K antagonists (VKA) due to improved pharmacologic properties, fewer
drug interactions and rapid onset of action. The objective of this review was to assess whether DOACs are the
alternative for VKA in subjects with mild-to-moderate chronic kidney disease (CKD).
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